Clopidogrel: Side Effects, Uses, Dosage, Interactions, Warnings

what is the drug clopidogrel

For more information about the possible side effects of clopidogrel, talk with your doctor or pharmacist. They can give you tips on how to manage any side effects that may be concerning or bothersome. Clopidogrel belongs to a drug class called antiplatelet drugs. Platelets are a type of blood cell involved in blood clotting. In general, any medicine that can increase the risk of bleeding (such as aspirin, SSRI antidepressants [eg, citalopram, duloxetine, fluoxetine, venlafaxine], fish oils) may interact with clopidogrel. Plavix contains the active drug clopidogrel, which is a prodrug that is processed to active metabolites through the CYP450 enzymes.

Clopidogrel, Oral Tablet

In theory, PPI concentrations could be influenced by the coadministration of drugs that inhibit or induce CYP2C19 or CYP3A4. However, such interactions are unlikely to be clinically relevant. Although these findings may seem disconcerting, they are typical of the drug interaction literature more generally. This reflects the low quality of evidence—principally case reports and volunteer studies—that accounts for most of what we know about drug interactions. For information about the dosage of Plavix, including its strengths and how to take the drug, keep reading. If you’ve had an allergic reaction to Plavix or any of its ingredients, your doctor will likely not prescribe it for you.

Clopidogrel oral tablet and alcohol

Consult your pharmacist or local waste disposal company. Lab and/or medical tests (such as complete blood count) may be done while you are taking this medication. Clopidogrel can slow down the removal of other drugs from your body, which may affect how they work. Examples of affected drugs include repaglinide, tovorafenib, among others.

If I stop taking clopidogrel after one year, will I experience side effects such as withdrawal symptoms?

what is the drug clopidogrel

Before having any procedures done, you should tell your doctors or dentists that you’re taking clopidogrel. You may need to stop taking this drug for a short time before a procedure to prevent bleeding. Your doctor will let you know when to stop taking this medication and when it’s OK to take it again. Before taking clopidogrel, be sure to tell your doctor and pharmacist about all prescription, over-the-counter, and other drugs you take.

Other side effects of Clopidogrel

If you’re pregnant or may become pregnant, talk with your doctor about the benefits and potential risks of using Plavix during pregnancy. However, animal studies is baclofen addictive don’t always predict what will happen in humans. If you drink alcohol, talk with your doctor about how much is safe for you to drink while you’re taking Plavix.

This can lead to brain damage if it’s not treated right away. Plavix is approved to reduce the risk of heart attack and stroke in adults who’ve had a recent heart attack. Heart attacks occur when your heart doesn’t get enough blood flow because of blocked can cocaine kill you blood vessels or other heart problems. This results in a lack of oxygen in your heart muscle and causes damage in your heart. In a clinical study of people admitted to the hospital with ACS, some people were given Plavix in combination with aspirin.

This is because Plavix and blood thinner drugs each work to stop your blood from forming clots. Plavix and Effient are both brand-name drugs, but there are generic forms available for each drug. The generic form of Plavix 9 best online sobriety support groups is called clopidogrel, while the generic form of Effient is called prasugrel. A generic drug is an exact copy of a brand-name medication. The generic is considered to be just as safe and effective as the original drug.

A boxed warning alerts doctors and patients about drug effects that may be dangerous. There aren’t any herbs or supplements that have been specifically reported to interact with Plavix. However, you should still check with your doctor or pharmacist before using any of these products while taking Plavix. If you need to take something for pain relief while you’re using Plavix, your doctor may recommend that you take acetaminophen (Tylenol) instead of ibuprofen or other NSAIDs. This is because acetaminophen has a lower risk of causing bleeding when it’s taken with Plavix.

Plavix may cause mild side effects other than those listed above. (An active ingredient is what makes a drug work.) Plavix comes as a tablet you swallow. Remember, you shouldn’t change your dosage of Plavix without your doctor’s recommendation.

This genetic test will help your doctor decide if you should take clopidogrel. If you have this kind of genotype, this drug may not work for you. Below is a list of medications that can interact with clopidogrel. This list does not contain all drugs that may interact with clopidogrel.

They also may be able to recommend tools that can make it simpler to open lids. Other types of interactions, such as those with herbs, supplements, foods, lab tests, and vaccines, may also occur with clopidogrel. Clopidogrel can cause mild or serious side effects (also known as adverse effects). The following lists contain some of the key side effects that may occur while taking clopidogrel.

Taking these drugs together further increases your risk of bleeding, especially the risk of bleeding in your stomach. Researchers followed the people for up to 15 months to see if they would have a cardiovascular event, such as heart attack, stroke, or cardiovascular-related death. At the end of the study, 9.9% of people taking Effient and aspirin had experienced a cardiovascular event.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist.

  1. The combination of Plavix and aspirin is called dual antiplatelet therapy.
  2. You should not take aspirin with clopidogrel unless your doctor specifically advises you to do so.
  3. TTP is a serious condition in which blood clots form throughout the body.
  4. Bruising is common with medications, such as Plavix, that prevent your body from forming blood clots.
  5. If you have certain heart conditions, your doctor might suggest Plavix as a treatment option for you.

However, if it’s almost time for your next dose, just skip the missed dose and take your next dose at the usual time. Don’t take two doses of Plavix at the same to make up for a missed dose. Doing this may increase your risk of serious side effects.

what is the drug clopidogrel

There are no adequate studies of clopidogrel in pregnant women. If you need surgery or dental work, tell the surgeon or dentist ahead of time that you take Plavix. Clopidogrel tablets should be stored at a room temperature of 77° F (25° C) in a tightly sealed container away from light. If necessary, the drug may be kept at temperatures of 59° to 86° F (15° to 30° C) for short periods, such as while traveling with the drug.

This is because certain antidepressants and Plavix can each increase your risk of bleeding. Taking these drugs together further increases your risk of bleeding. Because of this, Effient isn’t recommended for use in these people. Effient is also approved to prevent blood clots from forming on or inside stents (mesh tubes) in people with ACS.

Mais artigos